Approx.1% of the Swiss population is affected by a clinical disease known as rheumatoid Arthritis (RA), making it the most common inflammatory rheumatism. Heredity plays an important role in the development of the disease. In fact, a person with a close relative with an autoimmune disease is 3 to 6 times more likely to be affected. This genetic predisposition is reinforced by certain environmental factors, such as tobacco consumption or certain eating behaviors. Interestingly, RA starts years before the first clinical symptoms appear. The SCREEN-RA focusses on an at risk population for RA, namely first degree relatives of patients with an autoimmune disease. Participants are seen initially to exclude an active rheumatic disease, answer various questionnaires and provide biologic samples (serum, DNA, RNA…). Thereafter, participants are followed annually, either only per email or in person. The primary outcome is the development of incident arthritis or full-fledged classifiable RA.

Allergologie/Immunologie, Rheumatologie

Epidemiologisch

Soziodemographie, Krankheit / Diagnose, Intervention / Therapie, Risiken / Gesundheitsrelevante Bedingungen

Aktiv, seit 2009

Patienten mit einem erhöhten Risiko an Polyarthritis oder einer Autoimmunerkrankung zu erkranken.

Periodisch, 1 an

National, Tessin, Bergregionen

Spitäler, Universitäten

Privat und öffentliche Hand

HUG
Finckh // 26 Avenue Beau-Séjour
1211 Genève 14